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| 2006 | | | | Publications | - Statistical Heterospectroscopy, an Approach to the Integrated Analysis of NMR and UPLC-MS Data Sets: Application in Metabonomic Toxicology Studies. Crockford, D. J.; Holmes, E.; Lindon, J. C.; Plumb, R. S.; Zirah, S.; Bruce, S. J.; Rainville, P.; Stumpf, C. L.; Nicholson, J. K. Anal. Chem.; (Accelerated Article); 2006; 78(2); 363 -371
- Assessment of analytical reproducibility of 1H NMR spectroscopy based metabonomics for large-scale epidemiological research: the INTERMAP Study.. Dumas ME, Maibaum EC, Teague C, Ueshima H, Zhou B, Lindon JC, Nicholson JK, Stamler J, Elliott P, Chan Q, Holmes E. Anal Chem. 2006;78(7):2199-208.
- E. Genome-wide association: a promising start to a long race. vans, D. and Cardon, L.R. (2006) Trends in Genetics, 22:350-354.
- Evaluating coverage of genome-wide association studies. Barrett, J.C. and Cardon , L.R. (2006). Nature Genetics, 38:659-652
- Serial pyrosequencing for quantitative DNA methylation analysis Tost, J., El Abdalaoui, H. and Gut, I.G. (2006) Biotechniques, 40, 721-726
- Microfluidic analysis of antibody specificity in a compact disc format, J. Eriksson, C., Agaton, L., Ek, B., Kånge, R., Sundberg, M., Uhlén, M., Gustavsson, M. & Hober, S. (2006) Proteome Research. 5, 1568-1574
- Statistical Search Space Reduction and 2-Dimensional Data Display Approaches for UPLC-MS in Biomarker Discovery and Pathway Analysis. Crockford, D. J.; Lindon, J. C.; Cloarec, O.; Plumb, R. S.; Bruce, S. J.; Zirah, S.; Rainville, P.; Stumpf, C. L.; Johnson, K.; Holmes, E.; Nicholson, J. K. Anal. Chem.; 2006, 78, 4398-4408
- Standards for systems biology. Brazma A, Krestyaninova M, Sarkans U. Nat Rev Genet. 2006 Aug;7(8):593-605
- Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice. Dumas ME, Barton RH, Toye A, Cloarec O, Blancher C, Rothwell A, Fearnside J, Tatoud R, Blanc V, Lindon JC, Mitchell SC, Holmes E, McCarthy MI, Scott J, Gauguier D, Nicholson JK. Proc Natl Acad Sci U S A. 2006;103(33):12511-6.
- Functional epistasis on a common MHC haplotype associated with multiple sclerosis. Gergersen, J.W., Kranc, K.R., Ke, X., Svendsen, P., Madsen, L.S., Thomsen, A.R., Cardon, L.R., Bell, J.I., Fugger, L. (in press). Nature.
- Analysis of Protein Expression in Cell Microarrays; A Tool for Antibody Proteomics. Andersson A-C, Stromberg S, Backvall H, Kampf C, Uhlen M, Wester K and Ponten F: J Histochem Cytochem. 2006 Dec;54(12):1413-23.
- Affibody molecules in protein capture microarrays: evaluation of multidomain ligands and different detection formats”, Renberg, B., Nordin, J., Merca, A., Uhlén, M., Feldwisch, J., Nygren, P.-Å. & Eriksson Karlström, A.Submitted manuscript, under revision.
- PASSIM - an open source software system for managing information in biomedical studies. Juris Viksna, Edgars Celms, Martins Opmanis, Karlis Podnieks, Peteris Rucevskis, Andris Zarins, Amy Barrett, Sudeshna Guha Neogi, Maria Krestyaninova, Mark I McCarthy, Alvis Brazma, Ugis Sarkans. BMC Bioinformatics. 2007 Feb 9;8(1):52 [Epub ahead of print]
| | | | Poster Presentations | - Open source customisable Patient and Sample System for Information Management for biomedical studies. Poster presentation. Maria Krestyaninova, Edgars Celms, Martins Opmanis, Karlis Podnieks, Peteris Rucevskis, Andris Zarins, Sudeshna Guha Neogi, Juris Viksna, Mark McCarthy, Alvis Brazma, Ugis Sarkans. HUGO's 11th Human Genome Meeting, 31May-3Jun, 2006.
- Optimization of Collection and Handling Preocedures for NMR-based Metabonomic Studies on Type II Diabetes and Insulin Resistance. Poster presentation at the 2nd Scientific Meeting of the Metabolomics Society, Boston, June 24 – 29, 2006
- Statistical Search Space Reduction and Data Display for Biomarker Discovery Using LC-MS Derek Crockford & Jeremy Nicholson. Poster presentation at the 2nd Scientific Meeting of the Metabolomics Society, Boston, June 24 – 29, 2006
- Systems biology: data integration of parallel transcriptomics and metabonomics in insulin resistance research reveals contribution of gut microbiota. Dumas ME, Barton RH, Cloarec O, Gauguier D, Nicholson JK. Poster presentation at the 2nd Scientific Meeting of the Metabolomics Society, Boston, June 24 – 29, 2006
- O-PLS-DA Analysis and Display for UPLC-MS Data: Metabonomics of Hydrazine Toxicity Derek Crockford & Jeremy Nicholson. Poster presentation at the 17th International Mass Spectrometry Conference, Prague, August 27 – September 1, 2006
- PASSIM - an open source software system for managing information in biomedical studies. Maria Krestyaninova, Juris Viksna, Edgars Celms, Martins Opmanis, Karlis Podnieks, Peteris Rucevskis, Andris Zarins, Sudeshna Guha Neogi, Mark McCarthy, Alvis Brazma, Ugis Sarkans. Poster presentation at the MGED9 meeting, Sep 7-10, 2006.
| | | | Oral Presentations | - Maxine Allen: MolPAGE case study presentation: Genomes to Systems conference, 22-24th March 2006, Manchester.
- Dumas, M:Metabonomics of insulin resistance. Invited lecture at Imperial College Diabetes Research Day, 24th April 2006, London (UK).
- Lon Cardon: Replication strategies for whole genome association studies. Biology of Genomes, Cold Spring Harbor (New York) May 10-14th 2006.
- Derek Crockford: Integration of UPLC-MS with other analytical methods by correlation of data sets. Invited speaker at the 54th American Society for Mass Spectrometry Conference, Seattle, May 28 – June 1, 2006
- Mark Jairaj: Oral presentation at ASMS conference in Seattle, May 28 - June 1 2006; Development and validation of a protein precipitation LC-MS method for the metabonomic analysis of rat plasma., Mark Jairaj K.Magnus Åberg, Henrik Toft Pedersen and Dorrit Baunsgaard, Novo Nordisk A/S
- Mark McCarthy: Human Genome Meeting 2006, Helsinki 31st May – 3rd June 2006
- Krestyaninova M. Array Express etc. Oral presentation at Rosetta Technology Forum, 4-6 June, 2006.
- Krestyaninova M. Data management in the MolPAGE project. Oral presentation at the 'Proteomics: Challenges and Emerging Technologies' Meeting, Sep 29, 2006.
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